Legally Reviewed and Fact Checked by: Emily Weinberger , Attorney
The introduction of injectable contraception (the “birth control shot”) in the 1960s was a welcomed development for women who enjoyed the convenience of a regular injection, especially compared to birth-control options like the pill that required daily use.
Manufactured by Pfizer, Depo-Provera is one of the most popular birth control shots, marketed as safe and effective. However, recent findings have raised serious concerns about its safety, particularly regarding the Depo-Provera cancer risk.
Can Depo-Provera Cause Cancer? The Evidence
In March 2024, a study revealed that prolonged use of the Depo-Provera shot (longer than 1 year) may significantly increase the risk of brain tumors known as meningiomas.
This groundbreaking research led to a growing wave of lawsuits claiming Pfizer failed to properly warn consumers of this cancer risk.
This emerging information about the Depo-Provera cancer risk has prompted many health experts to urge women to consider alternatives.
Read Pfizer’s Warnings and Precautions about Depo-Provera.
How Do Meningiomas Develop?
Meningiomas develop from the meninges, which are the three thin layers of tissue that cover and protect the brain and spinal cord. Specifically, they originate in the arachnoid cap cells of the arachnoid layer — the middle layer of the meninges.
Development Process:
- Genetic mutations or hormonal triggers cause abnormal growth in the meninges.
- These mutated cells multiply and form a tumor mass, typically slow-growing and often benign.
- Although not usually cancerous, their pressure on brain structures can cause serious neurological symptoms.
Potential Triggers for Meningioma Growth:
- Hormonal influences (especially progesterone, which is why they’re more common in women)
- Radiation exposure
- Genetic conditions like neurofibromatosis type 2 (NF2)
- Prolonged use of certain hormonal drugs — like Depo-Provera — may elevate risk, especially with extended use
Important: While most meningiomas are non-cancerous, they can still lead to life-altering complications depending on their size and location in the brain or spine.
If you or a loved one developed health issues after using Depo-Provera, you may be entitled to legal compensation.
What is a Meningioma?
A meningioma is a tumor that forms in the meninges — the protective layers around the brain and spinal cord. While typically benign, these tumors can cause serious health issues due to their location.
- Common symptoms include:
- Persistent headaches
- Blurred or double vision
- Memory loss or cognitive difficulty
- Balance problems
- Seizures
- Loss of hearing or smell
- Weakness in limbs
Treatments often include surgery or radiation, leading to major medical costs and emotional strain.
Other Health Symptoms Reported by Depo-Provera Users
While meningiomas are the only condition that may entitle you to legal recourse at this time, users have reported other long-term side effects such as:
- Hormonal imbalances: mood swings, migraines, weight gain
- Bone density loss: increased fracture and osteoporosis risk
- Vision disturbances: potential hormonal impact on eye health
Read about other Depo-Provera side effects.
Did Pfizer Adequately Warn Users?
Many lawsuits allege Pfizer failed to disclose critical safety risks, potentially prioritizing profit over public health. Critics say insufficient testing and ignored warning signs allowed the drug to reach millions without proper precautions.
Can You File a Depo-Provera Cancer Lawsuit?
You may qualify to file a claim if:
- You used Depo-Provera, Depo-SubQ Provera 104, or a generic equivalent for 12+ months
- You were diagnosed with a brain or spinal tumor (meningioma)
- You’ve undergone or scheduled surgery, radiation, or medical monitoring for the tumor
Steps for Filing a Depo-Provera Cancer Lawsuit
At Serling & Abramson, P.C., our process is streamlined and stress-free:
- Free case consultation
- Evidence collection (medical records, history of use)
- Filing before legal deadlines
- Decision phase: settle or go to trial
Click below to get started today.
The Time to Act is Now
Despite growing awareness, Pfizer has yet to update the Depo-Provera warning label. Many women continue to use the product unaware of the cancer risks.
Michigan and other states have strict statutes of limitation.
Don’t wait — take legal action now to protect your health and your rights.
FAQs About Depo-Provera and Cancer
What cancers are linked to Depo-Provera?
A: Meningiomas (brain tumors) have been most directly linked in recent studies, especially with prolonged use.
Is there a class action lawsuit against Pfizer?
A: Multiple lawsuits are ongoing, with potential for broader litigation. Contact a legal professional to see if you qualify.
How long do I have to file a claim?
A: It depends on your state’s statute of limitations. In Michigan, the window may be limited to just a few years from diagnosis.
Can I join if I used a generic Depo shot?
A: Yes — use of the authorized generic may still qualify under the same legal grounds.
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